Promethazine hydrochloride and codeine phosphate syrup is indicated for your momentary aid of coughs and higher respiratory signs and symptoms affiliated with allergy or the widespread chilly.

This medication may comprise sugar and/or Liquor. Caution is suggested Should you have diabetic issues, Alcoholic beverages dependence, or liver condition. Check with your medical professional or pharmacist about applying this product securely.

The effects of concomitant use or discontinuation of cytochrome P450 3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with codeine are complicated, necessitating watchful thing to consider of the results on the guardian drug, codeine, along with the Energetic metabolite, morphine.

To reduce the risk of dizziness and lightheadedness, get up slowly but surely when growing from a sitting or lying posture.

As a result of opportunity for promethazine to reverse epinephrine’s vasopressor result, epinephrine shouldn't be made use of to treat hypotension linked with promethazine overdose.

Never raise your dose or use this solution a lot more normally or for for a longer period than prescribed. Your affliction will never boost any a lot quicker, and also your threat of Negative effects will raise.

No official scientific tests are carried out in individuals with hepatic impairment Therefore the pharmacokinetics of Promethazine with Codeine Oral Answer Within this patient inhabitants are unfamiliar.

Considering that Promethazine VC with Codeine is employed when required, you might not be on a dosing schedule. Skip any skipped dose if It truly is Virtually time for the following dose. Usually do not use two doses at 1 time.

Severe, daily life-threatening, or fatal respiratory melancholy continues to be noted with the usage of opioids, including codeine, one of many Lively ingredients in Promethazine with Codeine Oral Solution. Codeine produces dose-connected respiratory despair by specifically performing around the brain stem respiratory Centre that controls respiratory rhythm and will deliver irregular and periodic breathing. Codeine is subject matter to variability in metabolism centered upon CYP2D6 genotype, which may result in an increased exposure to your active metabolite morphine [see WARNINGS AND PRECAUTIONS (5.three)]. Promethazine exerts a depressant impact on the respiratory Middle that is impartial of and additive to that of other respiratory depressants, like codeine [see WARNINGS AND PRECAUTIONS (5.

Will not boost your dose or use this products extra normally or for longer than prescribed. Your condition won't enhance any quicker, and your risk of side effects will increase.

This medication may perhaps cause you to additional sensitive for the Sunlight. Limit your time during the Solar. Prevent tanning booths and sunlamps. Use sunscreen and don protective clothes when outdoor. Convey to your health practitioner without delay if you have sunburned or have skin blisters/redness.

Administration of codeine could possibly be accompanied by histamine release and may be applied with caution in atopic kids.

Your threat of having this problem can be increased if you are taking PROMETHAZINE WITH CODEINE ORAL Alternative with certain other medicines that lower hypertension. When you have any of these symptoms though having PROMETHAZINE WITH CODEINE ORAL Resolution , sit or lie down. Will not transform Your system situation way too quickly. Get up gradually from sitting or lying down. Adrenal gland troubles. PROMETHAZINE WITH CODEINE ORAL Remedy may cause critical and existence-threatening adrenal gland issues. Your Health care supplier might do blood checks to check for adrenal gland complications. Simply call your healthcare service provider instantly In case you have any of those signs: nausea

The risk for critical respiration problems is better when you start this medication, or if you take the wrong dose click here or choose additional of this medication than prescribed. Having this medication with alcohol or other drugs that could potentially cause drowsiness or respiration complications may possibly cause quite severe side effects, like death. Also, other drugs can have an affect on the removal of the products out of your overall body, which can have an effect on how it really works.